Table 1 Association analysis of rs2544390 with gout
Sample set | Case genotypes, number (frequency) | Control genotypes, number(frequency) | Unadjusted | Adjusted | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
CC | CT | TT | T frequency | CC | CT | TT | T frequency | Allelic OR, (95% CI) | P | Allelic OR,(95% CI) | P | |
European Caucasian | 206(0.371) | 272(0.490) | 77(0.139) | 426 (0.384) | 95(0.337) | 125(0.443) | 62(0.220) | 249 (0.441) | 0.79 (0.64-0.97) | 0.02 | 0.73 (0.52-1.03) | 0.07 |
Eastern Polynesian | 63(0.168) | 166(0.444) | 145(0.388) | 456 (0.610) | 94(0.176) | 257(0.482) | 182(0.341) | 621 (0.583) | 1.11 (0.92-1.35) | 0.26 | 1.09 (0.82-1.44) | 0.54 |
Mixed Eastern Western Polynesian | 4(0.191) | 7(0.333) | 10(0.476) | 27 (0.643) | 3(0.167) | 9(0.500) | 6 (0.333) | 21 (0.583) | 1.25 (0.53-2.96) | 0.61 | 9.15 (0.96-87.65) | 0.05 |
Western Polynesian | 18(0.063) | 129(0.453) | 138(0.484) | 405 (0.711) | 24(0.145) | 66(0.400) | 75(0.455) | 216 (0.655) | 1.30 (0.97-1.75) | 0.08 | 1.21 (0.82-1.77) | 0.33 |
Ngati Porou Hauora | 25(0.120) | 93(0.447) | 78(0.375) | 249 (0.635) | 38(0.179) | 101(0.476) | 68 (0.321) | 237 (0.572) | 1.30 (0.98-1.73) | 0.07 | 1.25 (0.83-1.88) | 0.29 |