Symptoms and diseases | IBS | IBS/FMS | P value | IBS/FMS cases classified by Marsh stage | P value | ||
---|---|---|---|---|---|---|---|
 | (N = 125) | (N = 104) | (IBS vs. FMS) | Marsh stage 0 (N = 39) | Marsh stage 1 (N = 58) | Marsh stage 3 (N = 7) | (Marsh stages 1 and 3 vs. Marsh stage 0) |
Widespread pain | – | 104 (100) | NA | 39 (100) | 58 (100) | 7 (100) | 1.000 |
Digestive complaints | 125 (100) | 104 (100) | 1.000 | 39 (100) | 58 (100) | 7 (100) | 1.000 |
Fatigue | 31 (25) | 94 (90) | <0.001 | 35 (90) | 53 (91) | 6 (86) | 0.878 |
Sleep disturbances | 28 (22) | 87 (84) | <0.001 | 29 (74) | 52 (89) | 6 (86) | 0.134 |
Anxiety/depression | 77 (62) | 69 (66) | 0.273 | 22 (56) | 42 (72) | 5 (71) | 0.251 |
Skin problemsb | 31 (25) | 52 (50) | <0.001 | 20 (51) | 28 (48) | 4 (57) | 0.888 |
Cognitive dysfunction | 5 (4) | 37 (36) | <0.001 | 14 (36) | 20 (34) | 3 (43) | 0.908 |
Urinary urgency | 6 (5) | 30 (29) | <0.001 | 10 (26) | 18 (31) | 2 (29) | 0.848 |
Headachesc | 24 (19) | 29 (28) | 0.082 | 5 (13) | 21 (36) | 3 (43) | 0.028 |
Balance problems/dizziness | 9 (7) | 29 (28) | <0.001 | 10 (26) | 17 (29) | 2 (29) | 0.924 |
Joint stiffness | 2 (2) | 27 (26) | <0.001 | 9 (23) | 16 (28) | 2 (29) | 0.872 |
Paraesthesias | 4 (3) | 25 (24) | <0.001 | 9 (23) | 14 (24) | 2 (29) | 0.952 |
Osteoporosis | 7 (6) | 14 (13) | 0.034 | 2 (5) | 10 (17) | 2 (29) | 0.110 |
TMJ disorder | – | 13 (12) | NA | 5 (13) | 6 (10) | 2 (29) | 0.520 |
Restless legs syndrome | – | 13 (12) | NA | 3 (8) | 8 (14) | 1 (14) | 0.277 |
Sjögren syndrome | – | 8 (8) | NA | – | 7 (12) | 1 (14) | NA |
Raynaud syndrome | 1 (1) | 5 (5) | 0.069 | – | 5 (9) | 1 (14) | NA |
Tender points (scale 0 to 18) | – | 16.1 (1.9) | NA | 14.8 (1.2) | 16.9 (1.8) | 16.3 (2.4) | <0.001 |
FIQ score (scale 0 to 80) | – | 68 (9) | NA | 63 (7) | 70 (9) | 74 (3) | <0.001 |
HAQ score (scale 0 to 3) | – | 1.5 (0.6) | NA | 1.4 (0.5) | 1.6 (0.6) | 1.7 (0.6) | 0.298 |
SF-36 Physical Component (scale 0 to 100) | 44 (13) | 29 (5) | <0.001 | 30 (7) | 29 (1) | 27 (4) | 0.380 |
SF-36 Mental Component (scale 0 to 100) | 41 (13) | 29 (14) | <0.001 | 35 (10) | 25 (13) | 17 (4) | <0.001 |
VAS fatigue score (scale 0 to 10) | 3 (1) | 7 (2) | <0.001 | 7 (0.8) | 8 (1.5) | 8 (0.3) | 0.006 |
VAS digestive score (scale 0 to 100) | 31 (12) | 47 (8) | <0.001 | 46 (9) | 47 (9) | 48 (2) | 0.516 |
Gastrointestinal symptoms duration, years | 29 (5) | 29 (7) | 0.917 | 29 (5) | 29 (8) | 28 (9) | 0.905 |
Extraintestinal systemic symptom duration, years | – | 9 (2) | NA | 9 (2) | 9 (2) | 7 (4) | 0.813 |