From: Beyond pain in fibromyalgia: insights into the symptom of fatigue
Intervention | Design and sample | Scales used | Effect on fatigue |
---|---|---|---|
Conventional therapies | Â | Â | Â |
Cognitive behavioral therapy | One RCT comparing multidisciplinary treatment to treatment augmented with CBT (n = 83) of women with FM [71] | FIQ fatigue | Cannot draw conclusion |
Exercise - aerobic exercise | 1 single-arm study of women with FM, CFS, and CFIDS (n = 7) [72] | VAS fatigue | Cannot draw conclusion in single arm study, 2 meta-analyses found improvement, MCID cannot be determined |
2 meta-analyses of 28 RCTs (n = 2,494) [73] and 34 RCTs (n = 2,276) [74] | |||
Exercise - strength training | 1 RCT (n = 26) of postmenopausal women with FM [75] | VAS fatigue | Clinically meaningful improvement in 2 RCTs, cannot draw conclusion in 1 RCT |
1 double-arm study of aerobic versus strength training (n = 30) of women with FM [76] | |||
1 RCT (n = 21) of premenopausal women with FM [77] | |||
Multicomponent/multidisciplinary treatmenta | 2 single-arm studies (n = 305) of patients with FM [78, 79], 4 RCTs (n = 513) of patients with FM [80–83], 1 RCT (n = 855) in patients with FM, OA, and RA [84] | FIQ fatigue | Clinically meaningful improvement in 4 RCTs, no clinically meaningful improvement in 3 RCTs |
1 meta-analysis of 9 RCTs (n = 1119) [85] | VAS fatigue | Meta-analysis found no evidence for efficacy in long-term follow-up | |
Complementary and alternative medicine | Â | Â | Â |
Acupuncture | 1 meta-analysis of 7 RCTs (median treatment time 9 sessions, n = 385) [86] |  | No improvement |
Meditative movement therapies | 1 meta-analysis of 7 RCTs (n = 362) [87] |  | Improvement overall, in subgroup analysis, only yoga improved fatigue |