From: Influence of the ABCG2 gout risk 141 K allele on urate metabolism during a fructose challenge
Risk allele present, n = 23 | Risk allele absent, n = 51 | P | |
---|---|---|---|
Age, years | 26.8 (13.6) | 32.9 (16.5) | 0.13 |
Male sex, n (%) | 18 (78%) | 25 (49%) | 0.023 |
Body mass index, kg/m2 | 26.9 (4.9) | 27.8 (6.0) | 0.56 |
Waist circumference, cm | 93.0 (11.7) | 92.7 (17.9) | 0.94 |
Systolic blood pressure, mmHg | 127 (14) | 127 (18) | 0.99 |
Diastolic blood pressure, mmHg | 70 (8) | 72 (10) | 0.44 |
Serum urate | 0.41 (0.12) mmol/L | 0.34 (0.1) mmol/L | 0.018 |
(6.8 (2.0) mg/dL) | (5.7 (1.7) mg/dL) | ||
Serum urate, adjusted for sex | 0.37 (0.09) mmol/L | 0.34 (0.09) mmol/L | 0.21 |
(6.2 (1.5) mg/dL) | (5.7 (1.5) mg/dL) | ||
Serum creatinine, mmol/L | 0.084 (0.013) | 0.077 (0.016) | 0.088 |
Fractional excretion of uric acid, % | 6.25 (2.86) | 5.62 (1.78) | 0.26 |
Fractional excretion of uric acid, % adjusted for sex | 6.61 (2.06) | 5.4 (2.07) | 0.031 |
Serum glucose, mmol/L | 4.69 (0.38) | 4.69 (0.45) | 0.99 |
Māori or Pacific ancestry, n (%) | 16 (70%) | 33 (65%) | 0.79 |
Eastern Polynesian, n (%) | 4 (17%) | 19 (37%) | 0.11 |
Western Polynesian, n (%) | 12 (52%) | 14 (27%) | 0.064 |
European ancestry, n (%) | 7 (30%) | 18 (35%) | 0.79 |