Clinical disease activity and acute phase reactant levels are discordant among patients with active rheumatoid arthritis: acute phase reactant levels contribute separately to predicting outcome at one year

Table 3 Clinical and functional status at one-year follow-up by APR levels

	Neither APR elevated	APR levels discordant	Both APR elevated	P value
	n = 2,520	n = 1,058	n = 650
mHAQ	0.34 ± 0.42	0.42 ± 0.49	0.47 ± 0.54	<0.0001
CDAI	10.45 ± 10.74	11.34 ± 10.72	12.75 ± 11.87	<0.0001
Tender joints	3.04 ± 5.36	3.01 ± 4.88	3.55 ± 5.87	0.1125*
Swollen joints	2.93 ± 4.65	3.31 ± 4.72	4.03 ± 5.27	<0.0001*
Patient global assessment	28.50 ± 24.81	31.53 ± 26.13	31.74 ± 26.68	<0.0007
MD global assessment	16.02 ± 16.31	18.23 ± 17.19	19.73 ± 19.73	<0.0001

^*Log-linear model (Poisson) - χ² test. APR, acute phase reactant; mHAQ, modified Health Assessment Questionnaire; CDAI, Clinical Disease Activity Index.

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