Figure 6From: Decreased plasma levels of soluble CD18 link leukocyte infiltration with disease activity in spondyloarthritisCD18 expression and distribution of monocyte subsets in healthy controls (HCs) and patients with spondyloarthritis (SpA). (A) The cell membrane expression of CD18 on CD14+ CD16++ (non-classic) monocytes, CD14++ CD16+ (intermediate) monocytes, and CD14++ CD16- (classic) monocytes using peripheral blood mononuclear cells (PBMCs) from a representative HC with the gating strategy indicated. (B) The cell membrane expression of CD18 on non-classic monocytes, intermediate monocytes, and classic monocytes in PBMCs from 5 HCs and 10 patients with SpA. Bars indicate median and interquartile range. (C) The percentages of intermediate monocytes among all CD14+ monocytes in HLA-B27-positive SpA, HLA-B27-negative SpA, and HCs. PBMCs from the same 10 patients with SpA and 5 HCs were used. Bars indicate median and interquartile range. *P <0.05; **P <0.01; ****P <0.0001.Back to article page