| NN-negative | NN-positive | P-value |
---|---|---|---|
(n patients = 18) | (n patients = 31) | ||
(n samples = 144) | (n samples = 253) | ||
Mean age at first sample (SD)(*) | 37.7 (13.1) | 34.9 (12.8) | 0.47 |
% Female (n)(*) | 77.8 (14) | 83.9 (26) | 0.71 |
Ethnicity(*) | Â | Â | 0.41 |
% AC (n) | 27.8 (5) | 41.9 (13) | Â |
% C (n) | 61.1 (11) | 38.7 (12) | |
% Other (n) | 11.1 (2) | 19.3 (6) | |
Median anti-dsDNA IU/ml (IQR)(**) (†) | 29 (13, 97) | 82 (17, 171) | 0.18 |
Mean C3 g/l (SD)(**) | 1.0 (0.2) | 0.9 (0.3) | 0.10 |
Median Global BILAG score (IQR)(**) (†) | 5 (2, 8) | 5 (3, 10) | 0.22 |
% anti-Sm positive (n)(*) | 0.0 (0) | 35.5 (11) | 0.004 |
% anti-RNP positive (n)(*) | 27.8 (5) | 32.3 (10) | 1.00 |
% anti-Ro-positive (n)(*) | 38.9 (7) | 45.2 (14) | 0.77 |
% anti-La positive (n)(*) | 16.7 (3) | 9.7 (3) | 0.66 |
% on hydroxychloroquine (n)(**) | 42.1 (61) | 44.7 (113) | 0.66 |
% on immunosuppressants (n)(**) | 25.7 (37) | 63.2 (160) | 0.001 |
% on ≥5 mg/day corticosteroids (n)(**) | 68.1 (98) | 78.3 (198) | 0.31 |