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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Induced and pre-existing anti-polyethylene glycol antibody in a trial of every 3-week dosing of pegloticase for refractory gout, including in organ transplant recipients

Figure 4

Pre-infusion (trough) pUA as a marker for a significant antibody response to pegloticase. All pUA determinations obtained immediately prior to each infusion of pegloticase (nominally 21 days after the preceding infusion) are plotted. The dashed line at 6 mg/dL is shown as a reference. (A) Persistent responders (blue symbols). The open circles and open triangles represent data for the two PR who had single pre-infusion (trough) pUA values >6.0 mg/dL. (B) Transient responders (red symbols). The asterisks represent data for the single TR in whom any pre-infusion (trough) pUA <6 mg/dL was observed.

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Arthritis Research & Therapy

ISSN: 1478-6362

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