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Table 1 Patients in the Dartmouth RA Cohort a

From: Serum C-X-C motif chemokine 13 is elevated in early and established rheumatoid arthritis and correlates with rheumatoid factor levels

Patient demographics (N= 193)

Seronegative

Seropositive

Number of patients (%)

30 (16%)

163 (84%)

Average age, yr (range)

55.6 (29 to 72)

57.9 (19 to 92)

Females, n (%)

24 (80%)

115 (71%)

RA duration <2 yr

10 (33%)

41 (25%)

SE status, n

14

116

  SE alleles = 0

7

22

  SE alleles = 1

7

56

  SE alleles = 2

0

38

C4 status, n

14

111

  C4 copies <4

9

30

  C4 copies ≥4

5

81

Medication history, n

  

  No DMARDs

9

36

  Nonbiologic DMARDs

10

54

  TNF inhibitors

4

42

  Other biologics

7b

31c

  1. aC4, Complement 4; DMARD, Disease-modifying antirheumatic drug; RA, Rheumatoid arthritis; SE, Shared epitope; TNF, Tumor necrosis factor. bAbatacept (n = 1) and rituximab (n = 6). cAbatacept (n = 2), rituximab (n = 27), tocilizumab (n = 1) and tofacitinib (n = 1).
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Arthritis Research & Therapy

ISSN: 1478-6362

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