Figure 1From: Liver X receptors alpha gene (NR1H3) promoter polymorphisms are associated with systemic lupus erythematosus in Koreans Functional effect of the polymorphisms on transcriptional activity. (A, B) Relative luciferase production (ratio of luciferase production driven by the reporter construct to that by the promoter-less control vector, pGL3-Basic) in Hep3B cells (A) and COS-7 cells (B). (C, D) Relative luciferase production by stimulation with 200 ng/mL LPS, 3 μmol/L GW3965 and 5 μmol/L T0901317 in Hep3B cells (C) and COS-7 cells (D). The P value was determined by a paired t test. *P <0.05. LPS, lipopolysaccharide.Back to article page