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Table 2 Overall sensitivity and specificity of anti-centromere antibodies by indirect immunofluorescence in diagnosis of CREST [40]

From: The clinical relevance of autoantibodies in scleroderma

CREST versus:

Sensitivity (%)

Specificity (%)

Normal controls

65

99.9

Other connective tissue diseases

61

98

Primary Raynaud's phenomenon

60

83

SSc

61

84