Smoking–gender interaction and risk for rheumatoid arthritis

Table 3 Adjusted odds ratios for developing rheumatoid arthritis according to smoking and rheumatoid factor status in men

	Number of observations entering the multivariable model
Parameter	RA cases	Controls	Odds ratio* (95% CI)
All RA
Current smoking	306	418	1.2 (0.7–2.0)
Past smoking	234	306	2.0 (1.2–3.2)
RF-positive RA
Current smoking	181	418	1.5 (0.8–2.6)
Past smoking	140	306	2.3 (1.3–3.9)
RF-negative RA
Current smoking	125	418	0.8 (0.3–1.8)
Past smoking	94	306	1.5 (0.7–3.0)

*Odds ratios are expressed as the expected probability of having rheumatoid arthritis (RA) as compared with those who did not smoke. The confounders adjusted for in the multivariable logistic regression models included age, body mass index, number of years of education, Health Assessment Questionnaire disability index, general health assessment, and pain. CI, confidence interval.

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