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Table 1 Association of PADI4 SNP (recessive model) with Sharp/van der Heijde score of hands at 5-year disease duration in ACPA-negative RA patients

From: Response to `Peptidyl arginine deiminase type IV (PADI4) haplotypes interact with shared epitope regardless of anti-cyclic citrullinated peptide antibody or erosive joint status in rheumatoid arthritis: a case control study'

Factor

Beta (95% CI)

Pvalue

rs2240340, PADI4

0.72 (0.08-1.36)

0.0287

HLA-DRB1 SE

0.36 (0.01-0.73)

0.0587

RF

0.54 (0.05-1.02)

0.0316

  1. ACPA, Anti-citrullinated peptide antibody; CI, Confidence interval; PADI4, Peptidyl arginine deiminase type IV; RA, Rheumatoid arthritis; RF, Rheumatoid factor; SE, Shared epitope; SNP, Single-nucleotide polymorphism.
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Arthritis Research & Therapy

ISSN: 1478-6362

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