Fig. 2From: CDP7657, an anti-CD40L antibody lacking an Fc domain, inhibits CD40L-dependent immune responses without thrombotic complications: an in vivo studyInhibition of humoral immune response in Cynomolgus monkeys: comparison of antibody formats. Animals received a single i.v. dose of antibody or saline 2 days prior to administration of tetanus toxoid (TT); the doses were 20 mg/kg for the IgG antibodies and 40 mg/kg for the PEGylated formats (n = 6 for all groups). The IgG anti-TT titers in plasma samples were assessed from days 10 to 31Back to article page