Table 1 MicroRNAs in fibrosis
MicroRNA | Target gene | Pro- or anti-fibrotic | Tissue | References |
|---|---|---|---|---|
17-5p | Smad7 | Pro | Liver | [34] |
21 | Sprouty homolog-1, PTEN, SMAD7, STAT3, PPAR-α | Pro | Heart, skin, kidney | |
29, a,b,c | Collagen1A1, 1A2, 4A5, FBN, ELN1, PDGFR, TAB1, ADAM | Anti | Heart, skin, liver | |
33a | PPAR-α | Pro | Liver | [29] |
122 | P4HA1 | Anti | Liver | [59] |
129-5p | Collagen1A1 | Anti | Skin | [39] |
132 | MeCP2 | Anti | Liver | [41] |
133a | Collagens | Anti | Liver | [28] |
192 | ZEB1 | Pro | Kidney | [31] |
199b | DYRK1A | Pro | Heart | [51] |
199a-5p | CAV1 | Pro | Lungs, skin | [47] |
214 | CTGF | Anti | Liver | [70] |