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Table 5 Most frequent clinical manifestations in patients with SLE

From: The assessment of serum-mediated phagocytosis of necrotic material by polymorphonuclear leukocytes to diagnose and predict the clinical features of systemic lupus erythematosus: an observational longitudinal study

Clinical manifestation

Always positive PNC (n = 12 patients, 166 assessments)

Always negative PNC (n = 31 patients, 475 assessments)

Variable PNC (n = 26 patients, 459 assessments)

Glomerulonephritis

31.9 %

10.5 %a

6.5 %a

Arthritis

1.8 %b

16.6 %

6.1 %a,b

Mucocutaneous

24.7 %

21.3 %

13.9 %a,b

Alopecia

10.8 %

7.8 %

7.2 %

Hematologic

3.0 %c

1.1 %c

7.0 %b

SLEDAI-2K >1

57.8 %

48.8 %

44.7 %a,b

  1. SLEDAI-2K Systemic Lupus Erythematosus Disease Activity Index 2000
  2. aSignificant difference (p ≤ 0.05) compared with “Always positive PNC”
  3. bSignificant difference (p ≤ 0.05) compared with “Always negative PNC”
  4. cSignificant difference (p ≤ 0.05) compared with “Variable PNC”
  5. The 69 patients are grouped depending on the outcome of PNC assay (positive or negative) over time