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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: PD-L1-expressing neutrophils as a novel indicator to assess disease activity and severity of systemic lupus erythematosus

Fig. 1

Expression of programmed death ligand 1 (PD-L1), programmed death 1 (PD1), CD40, T cell immunoreceptor with Ig and immunoreceptor tyrosine-based inhibitory domains (TIGIT), CD80 and CD86 in neutrophils. a Gates were set on neutrophils based on CD15 and CD3; neutrophils were defined as CD15 +CD3− forward scatter (FSC) high, side scatter (SSC) high. b Systemic lupus erythematosus (SLE) patients had elevated frequency of PD-L1-expressing neutrophils compared with healthy controls (HC) (P <0.0001). c The frequency of PD1-expressing neutrophils was similar in HC and SLE patients (P = 0.7533). d The frequency of CD40-expressing neutrophils was similar in HC and SLE patients (P = 0.2173). e The frequency of TIGIT-expressing neutrophils was similar in HC and SLE patients (P = 0.1122). f The frequency of CD80-expressing neutrophils was similar in HC and SLE patients (P = 0.8927). g The frequency of CD86-expressing neutrophils was similar in HC and SLE patients (P = 0.8928)

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Arthritis Research & Therapy

ISSN: 1478-6362

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