Table 2 Characteristics of patients fulfilling the ASAS axial spondyloarthritis classification criteria starting a second tumor necrosis factor inhibitor
Parameter | Number of patients | PLR (n = 110) | SLR (n = 220) | AE (n = 88) | Other (n = 70) | p Value |
|---|---|---|---|---|---|---|
Male sex, % | 488 | 47.3 | 60.9 | 53.4 | 55.7 | 0.12 |
Age, years | 488 | 42.8 ± 10.2 | 43.2 ± 10.9 | 42.3 ± 11.8 | 44.2 ± 13.4 | 0.77 |
Radiographic axSpA, % | 388 | 66.7 | 77.4 | 82.5 | 87.9 | 0.02 |
HLA-B27–positive, % | 442 | 51.6 | 73.7 | 75.0 | 78.3 | <0.001 |
Elevated CRP, % | 285 | 34.8 | 37.0 | 52.0 | 30.8 | 0.15 |
ASDAS-CRP | 256 | 3.4 ± 0.9 | 3.1 ± 0.9 | 3.0 ± 1.2 | 2.7 ± 1.1 | 0.003 |
ASDAS-ESR | 233 | 3.2 ± 0.8 | 2.8 ± 0.8 | 2.8 ± 1.2 | 2.7 ± 1.2 | 0.08 |
BASDAI | 275 | 6.1 ± 1.9 | 5.1 ± 2.0 | 4.7 ± 2.4 | 4.6 ± 2.3 | <0.001 |
BASFI | 274 | 4.7 ± 2.5 | 4.1 ± 2.5 | 3.5 ± 2.4 | 3.0 ± 2.2 | 0.002 |
BASMI | 228 | 2.1 ± 1.7 | 2.3 ± 2.0 | 2.7 ± 2.3 | 2.9 ± 2.0 | 0.27 |
Peripheral arthritis, % | 487 | 36.7 | 35.5 | 26.1 | 21.4 | 0.06 |
Enthesitis heel, % | 488 | 40.0 | 33.2 | 26.1 | 22.9 | 0.06 |
Smokers, % | 471 | 73.4 | 58.4 | 72.3 | 55.7 | 0.01 |
DMARDs, % | 488 | 20.0 | 22.7 | 9.1 | 17.1 | 0.03 |
NSAIDs, % | 488 | 62.7 | 54.5 | 50.0 | 35.7 | 0.01 |
BMI, kg/m2 | 478 | 26.1 ± 4.6 | 25.7 ± 4.8 | 26.0 ± 4.7 | 26.2 ± 4.8 | 0.88 |
Years of education | 463 | 13.0 ± 3.2 | 13.5 ± 3.0 | 13.0 ± 2.9 | 13.9 ± 3.2 | 0.23 |