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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Concurrent validity of different functional and neuroproteomic pain assessment methods in the rat osteoarthritis monosodium iodoacetate (MIA) model

Fig. 5

Place escape/avoidance paradigm (PEAP) evolution after osteoarthritis induction (least squares mean ± standard error of the mean). The percentage of time spent on the PEAP dark side was statistically higher in the lidocaine-treated rats with monosodium iodoacetate (MIA-L) when compared to the rats injected with monosodium iodoacetate (MIA) (P = 0.07) and the sham group (P = 0.01) group. Data presented here were collected for the whole period of assessment (20 minutes) at each day, but the observed between-group differences were the most obvious during the intermediate periods 2 (5–10 minutes) and 3 (10–15 minutes)

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Arthritis Research & Therapy

ISSN: 1478-6362

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