| Patients (n) | K d (nM) | p Value | Bmax (fmol/mg of protein) | p Value |
---|---|---|---|---|---|
Disease activity patterns | |||||
 CQD/CAD | 46/18 | 1.96 ± 1.19/1.77 ± 0.89 | NS | 141.6 ± 48.9/76 ± 28.6 | < 0.0001 |
Organ involvement | |||||
 Renal, yes/no | 13/67 | 1.33 ± 0.59/1.94 ± 1.15 | 0.06 | 114 ± 45.05/120.8 ± 52.3 | NS |
 Neuropsychiatric, yes/no | 20/60 | 1.73 ± 0.81/1.88 ± 1.18 | NS | 103.85 ± 48.2/125 ± 51.2 | NS |
 Articular, yes/no | 46/34 | 1.79 ± 1.22/1.9 ± 0.9 | NS | 110.85 ± 49.3/131.8 ± 51.5 | 0.06 |
 Cutaneous, yes/no | 25/55 | 1.46 ± 0.71/1.89 ± 1.2 | NS | 105.60 ± 43.9/123.8 ± 53.7 | NS |
 Hematological, yes/no | 41/39 | 1.70 ± 0.89/1.98 ± 1.28 | NS | 116.85 ± 47.8/123.6 ± 54.5 | NS |
 Serositis, yes/no | 21/59 | 1.60 ± 1.3/1.9 ± 0.9 | NS | 92.86 ± 38.7/129.2 ± 51.6 | 0.0043 |
Serological parameters | |||||
 aCL, yes/no | 22/58 | 1.91 ± 1.01/1.81 ± 1.14 | NS | 134.04 ± 52.55/114.27 ± 47.3 | NS |
 Anti-β2-GPI, yes/no | 9/71 | 1.59 ± 0.46/1.87 ± 1.15 | NS | 116.11 ± 53.15/120.2 ± 51.1 | NS |
 LA, yes/no | 28/52 | 1.92 ± 1.20/1.8 ± 1.05 | NS | 109.03 ± 51.60/125.5 ± 50.2 | NS |
 ENA, yes/no | 58/22 | 1.92 ± 1.15/1.77 ± 1.07 | NS | 114,5 ± 47.34/123.1 ± 53.52 | NS |
 Hypocomplementemia, yes/no | 53/27 | 1.57 ± 0.78/2.15 ± 1.32 | NS | 97.88 ± 39.25/145.08 ± 51.78 | < 0.0001 |
 Anti-dsDNA, yes/no | 41/39 | 1.65 ± 1.01/2.31 ± 1.18 | 0.008 | 106.26 ± 48.42/153.04 ± 41.76 | < 0.0001 |
Treatments | |||||
 Corticosteroids, 2.5 up to 12.5 mg/day, yes/no | 67/13 | 1.83 ± 1.17/1.88 ± 0.63 | NS | 113.12 ± 50.30/153.69 ± 41.47 | 0.0078 |
 Hydroxychloroquine, 200 mg/day, yes/no | 48/32 | 1.93 ± 1.07/1.69 ± 1.13 | NS | 126.89 ± 51.09/108.93 ± 49.72 | NS |
 Immunosuppressants or induction therapy, yes/no | 25/55 | 1.98 ± 1.19/1.54 ± 0.8 | NS | 124.31 ± 48.04/110.15 ± 56.46 | NS |
 Anticoagulants, yes/no | 11/69 | 2.01 ± 1.47/1.81 ± 1.04 | NS | 128.91 ± 64.01/128.91 ± 64 | NS |
 Antiaggregants, yes/no | 33/47 | 2.03 ± 1.24/1.7 ± 0.97 | NS | 123.39 ± 50.61117.13 ± 51.66 | NS |