Fig. 1

Proportions of CD14^brightCD16+, CD14^dimCD16+, and CD14^brightCD16- monocytes in peripheral blood obtained from patients with rheumatoid arthritis (RA) and from healthy volunteers at baseline (0 W) and 12 weeks (12 W). CD14^brightCD16-/CD14^brightCD16+/CD14^dimCD16+ monocytes were identified by flow cytometry. The proportion of the three subsets of monocytes in patients with RA at baseline and 12 weeks (n = 35) was compared with that in healthy volunteers (HV) (n = 14). Statistical analysis, Wilcoxon rank sum test. Proportions of CD14^brightCD16- and CD14^brightCD16+ were significantly different. N.S. not significant