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Table 2 Univariate Cox regression analysis for ECG-4 and ECG-5

From: Prevalence and associated factors of resting electrocardiogram abnormalities among systemic lupus erythematosus patients without cardiovascular disease

 

ECG-4

ECG-5

Variables

HR (95% CI)

p

HR (95% CI)

p

Non-Caucasian

1.91 (1.27–2.86)

0.002

1.63 (1.11–2.37)

0.012

Gender (male)

1.13 (0.62–2.07)

0.68

1.19 (0.68–2.09)

0.53

Age

1.03 (1.007–1.05)

0.01

1.02 (1.004–1.05)

0.02

Disease duration

1.06 (1.03–1.09)

0.0007

1.05 (1.014–1.09)

0.006

Hypertension within 5 years prior to ECG

0.88 (0.49–1.57)

0.67

0.91 (0.52–1.58)

0.73

Hyperlipidemia on statins ever before ECG

0.59 (0.30–1.13)

0.11

0.54 (0.29–1.01)

0.05

Ever smoked before ECG

0.72 (0.39–1.35)

0.31

0.75 (0.42–1.35)

0.34

Diabetes 3 years before ECG

0.75 (0.27–2.04)

0.09

0.75 (0.27–2.048)

0.57

SLEDAI-2 K

1.05 (1.012–1.013)

0.01

1.05 (1.01–1.09)

0.008

AMS 2 years prior to ECG

1.08 (1.02–1.13)

0.005

1.08 (1.03–1.13)

0.003

SDI

1.23 (1.07–1.41)

0.003

1.21 (1.06–1.39)

0.006

Cumulative glucocorticoids

1.007 (1.001–1.01)

0.02

1.007 (1.001.013)

0.02

Treated with antimalarials

2.27 (1.12–4.59)

0.02

2.11 (1.11–4.04)

0.02

Treated with immunosuppressives

2.15 (1.21–3.83)

0.009

2.06 (1.19–3.55)

0.009

Coombs

1.19 (0.81–1.76)

0.37

1.19 (0.83–1.73)

0.33

Anti-Jo1

0.65 (0.26–1.63)

0.36

0.71 (0.30–1.64)

0.41

Anti-La

0.79 (0.47–1.34)

0.39

0.8 (0.49–1.31)

0.38

Anti-RNP

1.18 (0.791.74)

0.41

1.24 (0.86–1.79)

0.24

Anti-Ro

0.81 (0.56–1.18)

0.27

0.79 (0.55–1.14)

0.21

Anti-Scl70

0.49 (0.15–1.59)

0.24

0.45 (0.14–1.44)

0.19

Anti-Smith

1.43 (0.89–2.27)

0.13

1.44 (0.93–2.22)

0.11

ANCA

0.63 (0.32–1.21)

0.17

0.63 (0.34–1.18)

0.15

Anti-ds DNA

1.52 (1.02–2.29)

0.041

1.48 (1.01–2.16)

0.04

ANA

0.86 (0.38–1.97)

0.72

0.74 (0.36–1.53)

0.42

APLA

0.85 (0.53–1.35)

0.48

0.73 (0.49–1.23)

0.29

  1. AMS adjusted mean SLEDAI-2 K, CI confidence interval, ECG electrocardiogram, HR hazard ratio, SDI SLICC/American College of Rheumatology Damage Index, SLE systemic lupus erythematosus, SLEDAI-2 K SLE Disease Activity Index 2000