| Healthy control subjects (n = 20) | ANA+ no symptoms (n = 38) | UCTD (n = 28) | SARD (n = 58) | SSc (n = 26) | SLE (n = 6) | SS (n = 23) | DM/MCTD (n = 3) |
---|---|---|---|---|---|---|---|---|
Female sex, n (%) | 18 (90) | 37 (97.4) | 27 (96.4) | 54 (93.1) | 24 (92.3) | 6 (100) | 21 (91.3) | 3 (100) |
Age, years, mean ± SD | 41 ± 12.4 | 44.1 ± 14.3 | 47.5 ± 15.4 | 51.5 ± 14.4 | 52.8 ± 14.7 | 39 ± 12.3 | 54.8 ± 12.7 | 39.3 ± 6.6 |
Anti-malarials, n (%) | 0 (0) | 5 (13.2) | 4 (14.3) | 7 (12.1) | 2 (7.7) | 2 (33.3) | 2 (8.7) | 1 (33.3) |
Ethnicity, n (%) | ||||||||
 Caucasian | 9 (45) | 23 (60.5) | 20 (71.4) | 41 (70.7) | 18 (69.2) | 4 (66.7) | 17 (73.9) | 2 (66.7) |
 African | 1 (5) | 4 (10.5) | 3 (10.7) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
 Asian | 1 (5) | 1 (2.6) | 3 (10.7) | 3 (5.2) | 1 (3.8) | 0 (0) | 2 (8.7) | 0 (0) |
 Southeast Asian | 3 (15) | 5 (13.2) | 0 (0) | 7 (12.1) | 3 (11.5) | 2 (33.3) | 2 (8.7) | 0 (0) |
 Filipino | 4 (20) | 1 (2.6) | 1 (3.6) | 4 (6.9) | 3 (11.5) | 0 (0) | 0 (0) | 1 (33.3) |
 Hispanic | 1 (5) | 1 (2.6) | 1 (3.6) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
 Other | 1 (5) | 3 (7.9) | 0 (0) | 3 (5.2) | 1 (3.8) | 0 (0) | 2 (8.7) | 0 (0) |
Specific antibodies, n (%) | ||||||||
 dsDNA | 0 (0) | 2 (5.3) | 4 (14.3) | 9 (15.5) | 3 (11.5) | 2 (33.3) | 3 (13.0) | 1 (33.3) |
 Ro | 0 (0) | 7 (18.4) | 8 (28.6) | 30 (51.7) | 4 (15.4) | 3 (50) | 23 (100) | 0 (0) |
 La | 0 (0) | 2 (5.3) | 4a (14.3) | 18 (31.0) | 0 (0) | 1 (16.7) | 17 (73.9) | 0 (0) |
 Sm | 0 (0) | 0 (0) | 2 (7.1) | 3 (5.2) | 0 (0) | 2 (33.3) | 0 (0) | 1 (33.3) |
 Sm/RNP | 0 (0) | 0 (0) | 5 (17.9) | 6 (10.3) | 2 (7.7) | 2 (33.3) | 0 (0) | 2 (66.7) |
 RNP | 0 (0) | 4 (10.5) | 4 (14.3) | 8 (13.8) | 2 (7.7) | 3 (50) | 1 (4.3) | 2 (66.7) |
 Scl-70 | 0 (0) | 0 (0) | 2 (7.1) | 10 (17.2) | 7 (26.9) | 1 (16.7) | 2 (8.7) | 0 (0) |
 Jo-1 | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
 Centromere | 0 (0) | 1 (2.6) | 1 (3.6) | 17 (29.3) | 14 (53.8) | 1 (16.7) | 1 (4.3) | 1 (33.3) |
 Chromatin | 0 (0) | 2 (5.3) | 4 (14.3) | 6 (10.3) | 1 (3.8) | 3 (50) | 0 (0) | 2 (66.7) |