Table 2 Baseline levels of galectin-3, hyaluronan, and the type IIA collagen N-terminal propeptide
Marker | Reference interval | Total UA (n = 111) | Pre-RA (n = 23) | Non-RA (n = 88) | Controls (n = 120 or 87) | p value (pre-RA vs non-RA) | p value (pre-RA vs controls) | p value (non-RA vs controls) |
|---|---|---|---|---|---|---|---|---|
Galectin-3 (μg/l) | 1.65–7.54 | 4.1 (3.3–5.2) | 4.6 (3.8–5.5) | 4.0 (3.1–4.9) | 3.8 (3.0–4.8) | 0.03 | 0.009 | 0.56 |
Hyaluronan (μg/ml) | 2.42–77.02 | 15.1 (8.5–30) | 19.4 (8.5–30) | 14.75 (8.6–30) | 17.4 (10–25.8) | 0.64 | 0.75 | 0.61 |
PIIANP (μg/l) | 1327–4680 | 1800 (1439–2252) | 1704 (1439–2105) | 1801 (1436–2260) | 2189 (1788–2712) | 0.75 | 0.004 | 0.0001 |