| All subjects (n = 234) |
---|---|
Demographics, median (IQR) or n (%) | |
 Age in years | 11.6 (9.8–13.7) |
 Sex, male | 169 (72.2) |
 Race, Caucasian | 194 (82.9) |
 Family history of HLA-B27-associated disease | 36 (15.4) |
Clinical characteristics, median (IQR) or n (%) | |
 HLA-B27 positivity | 135 (59.2) |
 Active joint count | 2 (1–4) |
 Tender entheses count | 2 (1–4) |
 MRI-defined sacroiliitis (n = 45 with imaging) | 25 (55.6) |
 Polyarticular onset | 52 (22.2) |
 ANA-positive | 49 (23.4) |
 CRP, abnormal/elevated | 39 (26.9) |
 ESR, abnormal/elevated | 93 (45.8) |
Patient-/physician-reported outcomes, median (IQR) | |
 Physician global disease activity assessment (0–10) | 2.5 (2–4) |
 Juvenile Spondyloarthritis Disease Activity Index (JSpADA) (0–8) | 3 (2.5–4) |
 Juvenile Arthritis Disease Activity Score (cJADAS), excluding ESR (0–30) | 9 (5–14) |
 Patient/parent global disease activity assessment (0–10) | 4 (2–6) |
 Function (CHAQ) (0–3) | 0.563 (0–1) |
 Patient/parent pain assessment (0–10) | 4 (2–7) |