From: Lymphatic delivery of etanercept via nanotopography improves response to collagen-induced arthritis
Route of administration | Mean ± SD maximum serum concentration of etanercept, μg/mL (time of maximum concentration) | Mean ± SD serum concentration of etanercept, μg/mL after 36 h administration |
---|---|---|
SOFUSA™ (n = 6) | 18.28 ± 6.95 (2 h) | 4.91 ± 3.76 |
IV (n = 6) | 110.84 ± 15.03 (2 h) | 47.06 ± 4.81 |
119.62 ± 16.73 (8 h) | ||
ID (n = 6) | 31.08 ± 5.68 (25 h) | 20.65 ± 2.94 |
SC (n = 4) | 13.50 ± 3.21 (24 h) | 13.50 ± 3.21 |