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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis

Fig. 1

Phenotypic characteristics of the TgA86 mouse model. a, b TgA86 transgenic mice, starting from an early age, exhibit significantly reduced body weight (a) and body length (b) compared to wt littermates (data are presented as mean ± SEM; ***P < 0.0002; ****P < 0.0001). c Representative photos at 20 weeks of age, highlight joint swelling and digit distortion in the hind limbs of TgA86 mice (upper panel) as well as characteristic bendings of their tails (lower panel). d Sagittal views of whole-body CT images show the hyperkyphosis observed in 20-week-old and, more severely, in 36-week-old TgA86 mice

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Arthritis Research & Therapy

ISSN: 1478-6362

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