Fig. 3
Analysis for the Topology structure of the gene co-expression network. RNA was extracted from PBMCs and quantified by RT-qPCR. The gene co-expression networks of inactive TAK and active TAK were constructed respectively. The Pearson correlation coefficient of any 2 gene expression levels was calculated to construct a correlation matrix. A P value of less than 0.05 was considered significant. The blue edge indicates the correlation only exists in the active TAK group or inactive TAK group. The bold line indicates the linear correlation that has a greater Pearson’s r than 0.74 and a smaller P value than 0.01. A Rank the genes by the degree change value (Degreeactive − Degreeinactive). B Exclude the genes with a decreasing degree, and construct a network map using the other genes. C The linear correlations between genes which were indicated by bold lines in B