| Sodium bicarbonate (N = 86) | Citrate mixture (N = 86) | TaCCi mixture (N = 82) |
---|---|---|---|
Age, years | 42.0 (35.0–55.5) | 45.5 (35.0–55.5) | 47.0 (34.8–57.0) |
BMI, kg/m2 | 26.8 (24.8–29.0) | 27.2 (25.0–28.9) | 27.4 (25.3–29.1) |
Systolic blood pressure, mmHg | 135 ± 15.2 | 135 ± 15.5 | 140 ± 17.2 |
Diastolic blood pressure, mmHg | 86.8 ± 10.9 | 87.9 ± 10.8 | 89.1 ± 11.2 |
Nephrolithiasis, n (%) | 9 (10.5%) | 6 (6.98%) | 3 (3.66%) |
Renal cyst | 24 (27.9%) | 23 (26.7%) | 23 (28.0%) |
Tophi, n (%) | 8 (9.30%) | 4 (4.65%) | 3 (3.66%) |
Smoking, n (%) | 42 (48.8%) | 31 (36.0%) | 38 (46.3%) |
Drinking, n (%) | 51 (59.3%) | 33 (38.4%) | 41 (50.0%) |
Blood laboratory parameters | |||
 Serum urate, μmoI/L | 538 ± 68.3 | 533 ± 59.3 | 524 ± 68.1 |
 Triglyceride, mmol/L | 1.62 (1.16–2.81) | 1.76 (1.27–2.42) | 1.76 (1.21–2.56) |
 Total Cholesterol, mmol/L | 5.28 ± 0.98 | 5.07 ± 0.99 | 5.28 ± 1.03 |
 Fasting blood glucose, mmol/L | 5.83 (5.61–6.30) | 5.89 (5.53–6.39) | 5.87 (5.57–6.18) |
 HOMA-IR | 3.01 (2.36–4.70) | 4.19 (2.26–6.21) | 3.48 (2.34–5.57) |
 ALT, U/L | 24.0 (18.0–38.0) | 24.0 (18.0–40.0) | 26.0 (19.0–37.3) |
 AST, U/L | 21.0 (18.0–24.3) | 21.0 (18.0–27.0) | 21.5 (18.0–25.0) |
 Blood urea nitrogen, mmol/L | 4.95 (4.28–5.90) | 4.75 (4.18–5.90) | 5.00 (4.30–5.90) |
 Serum creatinine, μmoI/L | 81.5 (73.8–92.3) | 84.0 (76.0–90.0) | 84.0 (78.0–93.0) |
 eGFR, mL/(min·1.73 m2) | 94.6 ± 16.7 | 93.5 ± 16.1 | 91.5 ± 15.2 |
 Serum potassium, mmol/L | 4.30 (4.10–4.53) | 4.40 (4.10–4.50) | 4.30 (4.20–4.50) |
 Serum sodium, mmol/L | 143 (142–144) | 142 (142–144) | 142 (141–143) |
 Serum chlorine, mmol/L | 102 (100–104) | 102 (100–103) | 103 (102–104) |
 CRP, mg/L | 3.30 (2.40–4.50) | 3.60 (2.65–4.15) | 3.50 (2.40–4.20) |
Urine parameters | |||
 pH | 5.56 (5.32–5.77) | 5.42 (5.25–5.88) | 5.51 (5.34–5.72) |
 Proteinuria, n (%) | 8 (9.30%) | 9 (10.5%) | 5 (6.10%) |
 Hemoglobinuria, n (%) | 3 (3.49%) | 4 (4.65%) | 3 (3.66%) |
 UACR, mg/g | 3.01 (0.56–11.2) | 3.29 (0.44–10.3) | 7.42 (0.72–11.9) |