Fig. 2From: Association of biochemical markers with bone marrow lesion changes on imaging—data from the Foundation for the National Institutes of Health Osteoarthritis Biomarkers ConsortiumReceiver operating characteristic curves of biochemical markers for predicting the presence and absence of bone marrow lesions at baseline. A unadjusted and B adjusted for covariates. Serum type I, type II, and type III collagen degradation mediated by matrix metalloproteinase (MMP) cleavage (C1M, C2M, C3M), serum propeptide of type IIb collagen (hsPRO-C2), and serum metabolite of C-reactive protein (CRPM)Back to article page