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Table 2 Baseline and changes in bone marrow lesions over 24 months

From: Association of biochemical markers with bone marrow lesion changes on imaging—data from the Foundation for the National Institutes of Health Osteoarthritis Biomarkers Consortium

Bone marrow lesions, n (%)

Baseline

Change over 24 months

Maximum size

0

66 (11)

No change

226 (37.7)

1

223 (37.2)

Worsening by 1 grade

275 (45.7)

2

202 (33.7)

Worsening by ≥ 2 grades

99 (16.6)

3

109 (18.3)

Number of subregions affected

0

66 (11)

Improvement

72 (12)

1

102 (17)

No change

308 (51.3)

2

128 (21.3)

Worsening by 1 subregion

161 (26.8)

3

128 (21.3)

4

80 (13.3)

Worsening by ≥ 2 subregions

59 (9.8)

≥ 5

96 (16)