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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Lipoxygenase-derived oxylipins are enriched in anti-citrullinated protein antibody (ACPA)-positive individuals at risk for developing rheumatoid arthritis

Fig. 1

Distribution of fatty acids and differences in ACPA + and ACPA − FDR. The samples used for this analysis were collected in/after 2013. A Bar plots showing relative proportion of unsaturated (UFA) and saturated (SFA) fatty acids in all samples. B Bar plot showing relative proportions of mono-unsaturated (MUFA), polyunsaturated (PUFA), and omega-3, omega-6, omega-9, and omega-5 fatty acids. C Volcano plot of differentially expressed FAs between ACPA + and ACPA − FDR. Analyzed by pairwise Wilcoxon rank sum test and adjusted for multiple comparisons. Significant FAs are annotated on the graph (erucic acid = C22_1, eicosatetraenoic acid = C20_3n3). D The ratio between omega-6 (ω6) and omega-3 (ω3) FA in ACPA − and ACPA + FDR. Differences determined with Wilcoxon rank-sum test

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Arthritis Research & Therapy

ISSN: 1478-6362

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