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Table 3 Predictors of response (complete or partial) at both weeks 26 and 52 versus no response at all visits from logistic regression

From: Longitudinal patterns and predictors of response to standard-of-care therapy in lupus nephritis: data from the Accelerating Medicines Partnership Lupus Network

Predictor variable

Odds ratio estimate (95% confidence interval)

P value

First biopsy

3.12 (0.89–10.89)

0.075

Anti-dsDNA antibody positive

4.70 (1.19–18.51)

0.027

No Cyclophosphamide induction

5.08 (0.80–32.26)

0.084

UPCR > 25% decrease from baseline to week 12

7.37 (2.31–23.49)

 < 0.001

  1. Based on available data for responder adjudication and all covariates
  2. UPCR urine protein/creatine ratio, anti-dsDNA antibody anti-double-stranded DNA autoantibody