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Table 2 General information, 5-HTTLPR genotype and allele frequency

From: Interaction of 5-HTTLPR and SLE disease status on resting-state brain function

 

SLE (n = 51)

HC (n = 44)

χ2/T

P-value

Gender [n (%)]

  

3.70

0.05a

 Male

6 (11.80%)

12 (27.30%)

 Female

45 (88.20%)

32 (72.70%)

Age (year)

29.76 ± 9.65

31.14 ± 8.06

0.63

0.53b

Education (year)

13.06 ± 3.39

13.25 ± 3.80

 − 0.26

0.80b

5-HTTLPR genotype [n (%)]

  

0.10

0.75a

 L/L + L/S

26 (51.00%)

21 (47.70%)

  

 S/S

25 (49.00%)

23 (52.30%)

  

5-HTTLPR allele frequency

  

 < 0.01

0.10a

 L allele

29 (28.43%)

25 (28.41%)

  

 S allele

73 (71.57%)

63 (71.59%)

  
  1. SLE, systemic lupus erythematosus; HC, healthy control; n, number of cases
  2. a2 × 2 chi-square test
  3. bIndependent sample t-test