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Table 4 Gray matter function in SLE patients with different 5-HTTLPR genotypes

From: Interaction of 5-HTTLPR and SLE disease status on resting-state brain function

 

AAL brain area

L/L + L/S (n = 26)

S/S (n = 25)

T/Z

P-value

ReHo

Parietal_Inf_R

0.93 ± 0.09

0.88 ± 0.08

2.35

0.02

Hippocampus_R

0.99 ± 0.14

0.92 ± 0.08

2.36

0.02

Cingulum_Post_R

1.07 ± 0.09

1.01 ± 0.10

2.07

0.04

ALFF

Hippocampus_L

1.05 (0.96,1.15)

0.98 (0.92,1.02)

 − 2.13

0.03

Hippocampus_R

1.00 (0.87,1.06)

0.92 (0.85,0.95)

 − 2.13

0.03

fALFF

Parietal_Inf_R

0.96 ± 0.04

0.93 ± 0.03

2.87

0.01

Hippocampus_L

0.98 (0.96,1.01)

0.95 (0.93,0.99)

 − 2.62

0.01

Hippocampus_R

0.99 (0.97,1.03)

0.96 (0.95,0.99)

 − 2.86

 < 0.01

Cingulum_Post_L

0.99 ± 0.04

0.97 ± 0.04

2.07

0.04

Lingual_R

0.96 ± 0.02

0.94 ± 0.02

2.33

0.02

  1. L Left, R Right, n number of cases, T Test statistic for independent samples t-test, Z test statistic for Mann–Whitney U test