Group | Alcohol intake (units/week) | Association with serum urate (μmol/L) | Association with hyperuricaemia | Association with gout | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
β | SE | Β | P-value | OR | 95% CI | P-value | OR | 95% CI | P-value | ||
All participants | Â | N = 345,339 | N = 345,339 | N = 350,057 | |||||||
All alcohol | 0.49 | 0.01 | 0.12 | < 1.00 × 10−300 | 1.015 | 1.014, 1.015 | < 1.00 × 10−300 | 1.013 | 1.013, 1.014 | 1.16 × 10−173 | |
Beer | 0.75 | 0.01 | 0.12 | < 1.00 × 10−300 | 1.022 | 1.021, 1.023 | < 1.00 × 10−300 | 1.023 | 1.021, 1.024 | 3.86 × 10−285 | |
Spirits | 0.45 | 0.02 | 0.03 | 1.41 × 10−104 | 1.013 | 1.011, 1.016 | 9.14 × 10−39 | 1.006 | 1.002, 1.010 | 0.001 | |
Wine | 0.33 | 0.01 | 0.06 | < 1.00 × 10−300 | 1.009 | 1.008, 1.010 | 6.29 × 10−22 | 1.004 | 1.002, 1.006 | 3.62 × 10−7 | |
Men | Â | N = 163,469 | N = 163,469 | N = 167,653 | |||||||
All alcohol | 0.51 | 0.01 | 0.16 | < 1.00 × 10−300 | 1.015 | 1.014, 1.015 | < 1.00 × 10−300 | 1.014 | 1.013, 1.015 | 7.37 × 10−172 | |
Beer | 0.74 | 0.01 | 0.17 | < 1.00 × 10−300 | 1.021 | 1.021, 1.022 | < 1.00 × 10−300 | 1.023 | 1.021, 1.024 | 2.04 × 10−281 | |
Spirits | 0.40 | 0.03 | 0.03 | 1.74 × 10−51 | 1.011 | 1.009, 1.014 | 1.99 × 10−27 | 1.006 | 1.002, 1.009 | 0.002 | |
Wine | 0.31 | 0.01 | 0.07 | 8.33 × 10−217 | 1.009 | 1.008, 1.009 | 1.23 × 10−103 | 1.004 | 1.002, 1.006 | 6.79 × 10−7 | |
Women | Â | N = 181,870 | N = 181,870 | N = 182,404 | |||||||
All alcohol | 0.47 | 0.01 | 0.10 | < 1.00 × 10−300 | 1.018 | 1.016, 1.020 | 3.71 × 10−76 | 1.010 | 1.004, 1.017 | 0.002 | |
Beer | 0.95 | 0.03 | 0.06 | 1.26 × 10−197 | 1.041 | 1.036, 1.046 | 1.55 × 10−53 | 1.029 | 1.012, 1.045 | 7.05 × 10−4 | |
Spirits | 0.77 | 0.04 | 0.04 | 4.88 × 10−103 | 1.031 | 1.026, 1.037 | 5.31 × 10−30 | 1.021 | 1.006, 1.038 | 0.01 | |
Wine | 0.40 | 0.01 | 0.08 | < 1.00 × 10−300 | 1.013 | 1.011, 1.015 | 3.53 × 10−33 | 1.006 | 0.998, 1.014 | 0.12 |