Fig. 3

Genetic architecture of JIA. A Estimation of the three genetic architecture parameters for JIA, AID_ALL, and AID_SURE using Summary-data-based BayesS (SBayesS). The dots and horizontal bars represent the posterior means and standard errors, respectively. The red and orange colors represent SBayesS and SBayesS excluding HLA regions. B Cumulative local SNP heritability across the genome using heritability estimates from Summary statistics (HESS). Total SNP-based genes are indicated. The red color shows SNP heritability explained by the HLA region