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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: B cell receptor repertoire analysis in primary Sjogren’s syndrome salivary glands identifies repertoire features associated with clinical activity

Fig. 1

Integrated scRNAseq and BCRseq analysis of pSS patients. Integrated scRNAseq and scBCRseq analysis of B cells taken from paired peripheral blood and labial biopsies of pSS patients (N = 3). A Projection of peripheral blood B cells of each patient in UMAP space (N = 2032 cells). B Projection of labial gland B cells of each patient in UMAP space (N = 1446 cells). C Bar plot of the percentage composition of each sample by cell type. D, E Visualization of the size of the BCR clone that each cell belongs to, among peripheral blood (D) and labial gland (E) samples. F–K Heavy chain isotype usage rates within each B cell population in labial gland and peripheral blood samples, expressed as % of all cells

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Arthritis Research & Therapy

ISSN: 1478-6362

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