From: Distinct uric acid trajectories are associated with incident cardiac conduction block
Group | UA trajectories, HR(95%CI) | ||
---|---|---|---|
Low-stable | Moderate-stable | High-stable | |
Excluding participants with follow-up < 2 years (n = 64,296) | |||
 Cardiac conduction block | Ref | 1.30 (1.15–1.46) | 1.86 (1.56–2.22) |
 Atrioventricular block | Ref | 1.40 (1.13–1.73) | 2.96 (2.23–3.92) |
 Bundle branch block | Ref | 1.26 (1.09–1.46) | 1.41 (1.12–1.78) |
Excluding participants eGFR < 45 (mL/min/1.73m2) (n = 65,950) | |||
 Cardiac conduction block | Ref | 1.30 (1.15–1.46) | 1.84 (1.54–2.19) |
 Atrioventricular block | Ref | 1.38 (1.11–1.70) | 2.79 (2.10–3.70) |
 Bundle branch block | Ref | 1.27 (1.10–1.47) | 1.43 (1.14–1.81) |
Excluding participants with a history of gout (n = 66,565) | |||
 Cardiac conduction block | Ref | 1.30 (1.16–1.47) | 1.82 (1.52–2.18) |
 Atrioventricular block | Ref | 1.39 (1.12–1.72) | 2.87 (2.16–3.81) |
 Bundle branch block | Ref | 1.27 (1.10–1.47) | 1.37 (1.08–1.73) |
Excluding participants with UA data less than 4 times (n = 38,854) | |||
 Cardiac conduction block | Ref | 1.30 (1.11–1.52) | 1.71 (1.36–2.16) |
 Atrioventricular block | Ref | 1.29 (0.98–1.71) | 2.58 (1.80–3.70) |
 Bundle branch block | Ref | 1.30 (1.07–1.57) | 1.31 (0.97–1.78) |