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Table 2 Clinical features of IgG4-RD patients and control participants subjected to serum collagen type XV measurement

From: Single-cell RNA sequencing of submandibular gland reveals collagen type XV-positive fibroblasts as a disease-characterizing cell population of IgG4-related disease

 

HC

(N = 5)

IgG4-RD, inactive (N = 5)

IgG4-RD, active

(N = 10)

Age, median (IQR), years

69 (59–73)

69 (66–69)

65 (64–69.25)

Sex, female (%)

40

20

20

number of involved organs, median (IQR)

N.D.

1 (1–2)

2 (1.25–2)

*Serum IgG4, median (IQR), mg/dL

N.D.

397 (220–480)

1073 (437.5–1240)

*Serum IgG4 3 months after treatment, median (IQR), mg/dL

N.D.

N.D.

173 (93.5–252.75)

IgG4-RD responder index before treatment, median (IQR)

N.D.

0 (0–1)

11.5 (8.5–13.5)

IgG4-RD responder index 3 months after treatment, median (IQR)

N.D.

N.D.

1 (0.25–1.75)

  1. HC: healthy control, IgG4-RD: IgG4 related disease, N.D.: not determined
  2. *Serum IgG4 normal range: 11–121 mg/dL