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Fig. 7 | Arthritis Research & Therapy

Fig. 7

From: Fibroblast-like synoviocytes-derived exosomal circFTO deteriorates rheumatoid arthritis by enhancing N6-methyladenosine modification of SOX9 in chondrocytes

Fig. 7

Exosomal circFTO reduces the growth and migration and promotes the apoptosis of chondrocytes by targeting SOX9. (A) The impact of the exosomal circFTO-SOX9 axis on chondrocyte viability was assessed using the CCK-8 assay. (B) The effect of the exosomal circFTO-SOX9 axis on chondrocyte migration was investigated through Transwell assays. (C) The influence of the exosomal circFTO-SOX9 axis on chondrocyte apoptosis was examined using TUNEL assays. Data are presented as mean ± SD, n = 3; *p < 0.05, **p < 0.01, ***p < 0.001, ##p < 0.01, ###p < 0.001

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Arthritis Research & Therapy

ISSN: 1478-6362

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