Fig. 3

Timing of BCR depletion does not predict long-term clinical outcome but correlates with short-term disease activity. A-B Boxplot showing the changes in DAS28-score between month 1 (A) or month 3 (B) post-treatment and baseline in early or late depleting patients. Boxplots show the median and 25th and 75th interquartile, error bars show the range, and single data points are depicted in grey (*p ≤ 0.05, using Mann-Whitney test in A and unpaired t-test in B)