Table 3 Adverse pregnancy outcome ratio according to the achievement of remission at conception

n

37

59

Overall APO (%)

26 (70.3)

23 (39.0)

< 0.01

0.27

0.11–0.65

< 0.01

0.28

0.11–0.70

< 0.01

Maternal APO (%)

15 (40.5)

11 (18.6)

0.032

0.34

0.13–0.85

0.021

0.33

0.12–090

0.030

Neonatal APO (%)

23 (62.2)

23 (39.0)

0.036

0.39

0.17–0.90

0.028

0.37

0.15–0.90

0.029

PROMISSE APO (%)

10 (27.0)

12 (20.3)

0.47

0.69

0.26–1.81

0.45

0.64

0.23–1.76

0.38

Flare during pregnancy (%)

8 (21.6)

2 (3.4)

0.13

0.03–0.64

Flare after delivery (%)

2 (6.7)

1 (1.9)

0.26

0.23–3.04

Gestational DM (%)

6 (16.2)

4 (6.8)

0.38

0.10–1.43

Preeclampsia (%)

3 (8.1)

3 (5.1)

0.61

0.12–3.18

Hypertensive disorders in pregnancy (%)

7 (18.9)

6 (10.2)

0.49

0.15–1.58

HELLP syndrome (%)

1 (2.7)

1 (1.7)

0.62

0.04–10.2

Oligohydramnios (%)

6 (16.2)

2 (3.4)

0.19

0.04–0.97

Maternal death (%)

0 (0.0)

0 (0.0)

NA

NA

Live birth (%)※

29 (78.4)

54 (91.5)

2.98

0.89–9.94

Total duration of gestation (days)

262.0 [242.0, 271.0]

268.0 [262.0, 276.0]

NA

NA

Preterm birth (%)

6 (18.2)

8 (14.8)

0.78

0.25–2.5

Spontaneous abortion (%)

1 (2.8)

2 (3.4)

1.25

0.11–14.3

Missed abortion (%)

3 (8.1)

1 (1.8)

0.20

0.02–2.02

Iatrogenic abortion (%)

5 (13.5)

2 (3.4)

0.23

0.04–1.22

Still birth (%)

0 (0.0)

0 (0.0)

NA

NA

Height at birth (cm)

46.0 [43.8, 48.0]

48.0 [46.5, 49.5]

NA

NA

Weight at birth (g)

2472.0 [2202.0, 2896.0]

2716.0 [2476.5, 3013.8]

NA

NA

Low birth weight (%)

15 (51.7)

15 (27.8)

0.36

0.14–0.92

SGA (%)

6 (20.7)

8 (14.8)

0.67

0.21–2.15

Apgar score (1 m)

8.00 [8.00, 8.00]

8.00 [8.00, 8.00]

NA

NA

Apgar Score (5 m)

9.00 [9.00, 9.00]

9.00 [9.00, 9.00]

NA

NA

Apgar.score.1 m > 7 (%)

27 (93.1)

53 (98.1)

3.93

0.34–45.3

Apgar.score.5 m > 7 (%)

29 (100.0)

54 (100.0)

NA

NA

Major malformation

1 (3.4)

1 (1.9)

0.53

0.32–8.80

Death of neonate

0 (0.0)

0 (0.0)

NA

NA