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Table 2 The minimum PLT value during follow-up and the treatment response of 350 SLE-TP patients with different aPLs

From: Antiphospholipid antibodies as potential predictors of disease severity and poor prognosis in systemic lupus erythematosus-associated thrombocytopenia: results from a real-world CSTAR cohort study

 

aPLs+(n = 194)

 

aPLs-

(n = 156)

P

1 aPL+

(n = 75, 38.7%)

2 aPLs+

(n = 51, 26.2%)

3 aPLs+

(n = 68, 35.1%)

aPLs + total

Minimum platelet count (×109/L)

45(21,73)

32(11,71)

31.5(12.5,50)

37(15,64)

51(27,76)

0.002

 Severe(<20 × 109/L), n(%)

16(21.3)

19(37.3)

22(32.4)

57(29.4)

28(17.9)

0.010

 Moderate(20–50 × 109/L), n(%)

27(36.0)

13(25.5)

26(38.2)

66(34.0)

48(30.8)

 Mild(50–100 × 109/L), n(%)

32(42.7)

19(37.3)

20(29.4)

71(36.6)

80(51.3)

Latest platelet count (×109/L)

125(85,211)

147(90,222)

100.5(64,172)

123(79,209)

141(82,212)

0.361

 CR, n(%)

69(92.0)

42(82.4)

55(80.9)

166(85.6)

135(86.5)

 

 R, n(%)

1(1.3)

2(3.9)

7(10.3)

10(5.2)

1(0.6)

0.021

 NR, n(%)

5(6.7)

7(13.7)

6(8.8)

18(9.3)

20(12.8)

 

Loss of CR or R, n(%)

41(54.7)

28(54.9)

44(64.7)

113(58.2)

69(44.2)

0.009

  1. Note:CR, complete response,is defined as platelet count recovered to at least 100 × 109/L. R, response, is defined as the restoration of the platelet count to a range 30 and 100 × 109/L and along with at least a twofold increase from the baseline count. NR, nonresponse,is recorded when the platelet count remained below 30 × 109/L or did not double from the baseline count. Loss of CR or R, is denoted by a platelet count falling below 100 × 109/L (for those in CR), or dropping below 30 × 109/L or failing to achieve at least a twofold increase from the baseline count (for those in R)
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Arthritis Research & Therapy

ISSN: 1478-6362

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