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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Nintedanib downregulates the profibrotic M2 phenotype in cultured monocyte-derived macrophages obtained from systemic sclerosis patients affected by interstitial lung disease

Fig. 5

TGFβ1 protein synthesis of cultured MDMs from SSc-ILD patients. Evaluation by ELISA of the release of active TGFβ1 in conditioned medium of cultured monocytes-derived macrophages obtained from 10 SSc-ILD patients. Cultured MDMs were maintained in normal growth medium without any treatment (black bar), treated with nintedanib at the concentration of 0.1µM (light gray bar), treated with nintedanib at the concentration of 1µM (dark gray bar) for 3, 16, and 24 h. Data are reported as median with range

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