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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Targeting STAT6-mediated synovial macrophage activation improves pain in experimental knee osteoarthritis

Fig. 2

Knee pressure pain and hindpaw withdrawal thresholds. Pressure pain threshold as measured by pressure application measurement of Veh-lip (control) (A), Clod-lip (B), STAT1i-lip (C), and STAT6i-lip (D) treatment at pre-surgical baseline (0), and 4-, 8- and 12-weeks post OA induction. Hindpaw withdrawal threshold as measured by electronic von Frey of Veh-lip (control) (E), Clod-lip (F), STAT1i-lip (G), and STAT6i-lip (H) treatment at pre-surgical baseline (0), and 4-, 8- and 12-weeks post OA induction. The y-axis represents force (grams, g) applied to the hindpaw before withdrawal and the x-axis time in weeks. Mean with 95% confidence intervals are displayed. Significant differences versus baseline (*) and versus control (Veh-lip) (+) are shown (P <0.05)

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Arthritis Research & Therapy

ISSN: 1478-6362

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