Fig. 5

Macrophage quantification in the synovial intima and sub-intima. Representative confocal images of anti-CD68 stained (green) macrophages at 4- and 12-weeks post surgery (A). The scale bar represents 25μm. The white line separates the edge of the synovium and joint space and red line the interface between intima and subintima. White arrows highlight CD68 positive cells. Cell density in the intima 4- (●) (B) and 12-weeks (◼) (C) and subintima 4- (●) (D) and 12-weeks (◼) (E) post surgery with comparisons to Veh-lip. Mean with 95% confidence intervals are displayed, ** p<0.01, * p<0.05