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Table 4 Association of internalizing symptoms with clinical and sociodemographic parameters, adjusted OR and 95% CI

From: Anxiety and depression symptoms in adolescents and young adults with juvenile idiopathic arthritis: results of an outpatient screening

 

aOR (adjusted for date of survey)

p

Sociodemographic / anthropometric data

  

 Age

1.09 (1.01–1.18)

0.026

 Female gender

2.33 (1.53–3.56)

< 0.0001

Overweight > 90. Percentile vs. ≤90 p

1.39 (0.92–2.09)

0.120

JIA specific data

  

 PGA score*

0.96 (0.87–1.05)

0.385

 RF-positive polyarthritis

 RF-negative polyarthritis

 Systemic JIA

 Persistent oligoarthritis

 Extended oligoarthritis

 Psoriatic arthritis

 Enthesitis-related arthritis

2.31 (0.59–9.11)

2.30 (0.72–7.45)

3.76 (0.91–15.47)

2.13 (0.66–6.79)

2.30 (0.70–7.54)

2.22 (0.64–7.76)

3.01 (0.91–9.93)

0.231

0.161

0.066

0.203

0.169

0.211

0.070

Patient-reported data

  

 Functional disability (C-HAQ)*

3.36 (1.98–5.72)

< 0.0001

 Well-being*

1.17 (1.07–1.27)

< 0.0001

Lifestyle factors

  

 Regular sports participation

0.69 (0.49–0.98)

0.039

  1. JIA, juvenile idiopathic arthritis; RF, rheumatoid factor; cJADAS-10, 10-joint clinical Juvenile Arthritis Disease Activity Score; C-HAQ, Childhood Health Assessment Questionnaire. Internalizing symptoms defined as score of ≥ 7 in at least one of two screening instruments (PHQ-7/GAD-7). GAD-7 (score 0–21), Generalized Anxiety Disorder Scale-7; PHQ-9 (score 0–27), Patient Health Questionnaire-9. A logistic regression model was performed. *higher scores indicate worse PGA, functional disability, and well-being.