Figure 4

Established rheumatoid arthritis: progression of structural joint damage. Infliximab (IFX) plus methotrexate (MTX) significantly reduces progression of structural joint damage compared with MTX alone, after 1 year of treatment. All patients received concomitant MTX [32]. P < 0.001 for all doses and courses. vdH-S, van der Heijde–Sharp.