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Arthritis Research & Therapy


  1. Content type: Commentary


    Authors: Kazuhiko Yamamoto, Yeong-Wook Song and Zhan-guo Li

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Professor Christopher Buckley, University of Birmingham and University of Oxford, UK
Professor Harris Perlman, Northwestern University, USA

Aims and scope

Established in 1999, Arthritis Research and Therapy is an international, open access, peer-reviewed journal, publishing original articles in the area of musculoskeletal research and therapy as well as, reviews, commentaries and reports.
A major focus of the journal is on the immunologic processes leading to inflammation, damage and repair as they relate to autoimmune rheumatic and musculoskeletal conditions, and which inform the translation of this knowledge into advances in clinical care.
Original basic, translational and clinical research is considered for publication along with results of early and late phase therapeutic trials, especially as they pertain to the underpinning science that informs clinical observations in interventional studies.

Review series: New technologies

Written by renowned experts in the field, this collection of open access Review articles explores the use of RNA sequencing, cytometry, metabolomics and next-generation DNA sequencing in rheumatic disease.

Featured review: Fibroblast-like synoviocyte metabolism in the pathogenesis of rheumatoid arthritis

New Content ItemIn this review, Bustamante and colleagues show how fibroblast-like synoviocytes in RA patients differ from healthy synovial fibroblasts, not only in their marker expression, proto-oncogene expression, or their epigenetic changes, but also in their intracellular metabolism.
"Whether this truly constitutes an option to increase the drug armamentarium in rheumatic diseases beyond biological and kinase inhibitor therapies remains to be determined."


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